ig a
IgA
Serum IgA is monomeric, but IgA found in secretions is a dimer having a J chain. Secretory IgA also contains a protein called secretory piece or T- piece, this is made in epithelial cells and added to the IgA as it passes into secretions helping the IgA to move across mucosa without degradation in secretions.
Properties
1. It is the second most abundant Ig in serum
2. It is the major class of Ig in secretions- tears, saliva, colostrums, mucus, and is important in mucosal immunity.
3. It binds to some cells- PMN cells and lymphocytes
4. It does not normally fix complement.